.Net frameworks are resources used by programs and each 'version' contains unique elements - you need 'em all
Unlike some, I like the programs that use .Net. In a lot of cases you can install the programs on a USB drive and take them with you when you go. I have a series of utilities, such as password minder, a pixel ruler, a freeware screen grabber (that doesn'r require registration including with the Window's registry) and so on. It is a true 'plug and play' tech writing tool box.